Shiga-like toxin

From Academic Kids

Shiga-like toxin is Shiga toxin produced by the bacteria E. coli and also known as Verotoxin. In 1977, researchers in Ottawa rediscovered the Shiga toxin produced by Shigella dysenteriae in E. coli [1] (http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=338490). The E. Coli version was named Verotoxin because of the ability of the toxic protein to kill Vero (African green monkey kidney) cells in culture. Shortly after, the Verotoxin was referred to as Shiga-like toxin because of its similarities to Shiga toxin.

See also: E. coli O157:H7, Hemolytic-uremic syndrome, Shiga toxin

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